Multiple studies establish the relationship between eye rubbing and keratoconus. A group of cornea experts in Paris hoped to identify other risk factors that may lead to progression. They turned to a small subgroup of patients—those with severe KC in one eye and no evidence of disease in the other to learn more.
These data suggest that CXL should be considered as first line treatment in progressive disease. If the arrest of keratoconus progression induced by CXL is sustained in longer follow up, there may be particular benefit in avoiding a later requirement for contact lens wear or corneal transplantation.
Untreated keratoconus patients who are young or have steepest keratometry (Max-K) may be at increased risk of disease progression, new research published online in the British Journal of Ophthalmology suggests.